Difference between revisions of "Part:BBa K364332:Experience"
 
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[[Image:PXR,_Ecr2.jpg|450px|thumb|center|Test of pCDNA/pSB1A3-GAL4-PXR/EcR-LBD activity]]
 
[[Image:PXR,_Ecr2.jpg|450px|thumb|center|Test of pCDNA/pSB1A3-GAL4-PXR/EcR-LBD activity]]
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[[Image:Interact_3.jpg|400px|thumb|center|Test of PXR:RXR interaction]]
  
 
===User Reviews===
 
===User Reviews===

Latest revision as of 07:59, 27 October 2010

This experience page is provided so that any user may enter their experience using this part.
Please enter how you used this part and how it worked out.

Ligand

PXR is activated by a large number of endogenous and exogenous chemicals including steroids, antibiotics, antimycotics, bile acids, hyperforin, a constituent of the herbal antidepressant St. John's Wort, and many other herbal compounds.

PXR is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin.

Applications of BBa_K364332

Picture of Western blot: Gal4-PXR composite construct is highly expressed in the expression vector created from pSB1A3
Picture of Western blot: Gal4-PXR composite construct is highly expressed in the expression vector created from pSB1A3
Test of pCDNA/pSB1A3-GAL4-PXR/EcR-LBD activity
Test of PXR:RXR interaction

User Reviews

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