Difference between revisions of "Part:BBa K321003:Experience"
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===Applications of BBa_K321003=== | ===Applications of BBa_K321003=== | ||
| − | We used the CD3 zeta ITAM-containing intracelluar signaling domain as an activation module for our project. We used it in our chimeric antigen receptors. Specifically, we used CD3 zeta in our ANDN logic gate, and showed increased | + | We used the CD3 zeta ITAM-containing intracelluar signaling domain as an activation module for our project. We used it in our chimeric antigen receptors. Specifically, we used CD3 zeta in our ANDN logic gate, and showed increased killer cell activation with it when the target cell expressed its antigen alone. |
For our complete results, please refer to our wiki here: http://2010.igem.org/Team:UCSF/Project/Precision | For our complete results, please refer to our wiki here: http://2010.igem.org/Team:UCSF/Project/Precision | ||
Latest revision as of 02:49, 26 October 2010
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Applications of BBa_K321003
We used the CD3 zeta ITAM-containing intracelluar signaling domain as an activation module for our project. We used it in our chimeric antigen receptors. Specifically, we used CD3 zeta in our ANDN logic gate, and showed increased killer cell activation with it when the target cell expressed its antigen alone. For our complete results, please refer to our wiki here: http://2010.igem.org/Team:UCSF/Project/Precision
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UNIQ8194d94f98da1492-partinfo-00000000-QINU UNIQ8194d94f98da1492-partinfo-00000001-QINU