Difference between revisions of "Part:BBa K364314:Experience"
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how you used this part and how it worked out. | how you used this part and how it worked out. | ||
| − | ===Physiological functions of | + | ===Physiological functions of NHR-8=== |
| − | + | NHR-8 is required for gut function and may respond to the food signal. | |
| − | The nhr-8 gene mutants have abnormally low resistance to the toxins colchicine and chloroquine. | + | The nhr-8 gene mutants have abnormally low resistance to the toxins colchicine and chloroquine.This resembles the regulation of protective metabolic enzymes by xenobiotic-sensing nuclear receptors. |
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NHR-8 may thus mediate a subset of the resistance traits promoted by PGP-3. | NHR-8 may thus mediate a subset of the resistance traits promoted by PGP-3. | ||
| − | ===Possible applications of | + | ===Possible applications of NHR-8 LBD=== |
This LBD can be fused with different DBDs forming a composite hormone receptor for ligand regulated expression of specific genes and can also be a sensor for various lipid natured molecules. | This LBD can be fused with different DBDs forming a composite hormone receptor for ligand regulated expression of specific genes and can also be a sensor for various lipid natured molecules. | ||
Latest revision as of 18:17, 25 October 2010
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how you used this part and how it worked out.
Physiological functions of NHR-8
NHR-8 is required for gut function and may respond to the food signal.
The nhr-8 gene mutants have abnormally low resistance to the toxins colchicine and chloroquine.This resembles the regulation of protective metabolic enzymes by xenobiotic-sensing nuclear receptors.
NHR-8 may thus mediate a subset of the resistance traits promoted by PGP-3.
Possible applications of NHR-8 LBD
This LBD can be fused with different DBDs forming a composite hormone receptor for ligand regulated expression of specific genes and can also be a sensor for various lipid natured molecules.
Applications of BBa_K364314
User Reviews
UNIQ5d9b4bf261b03b66-partinfo-00000000-QINU UNIQ5d9b4bf261b03b66-partinfo-00000001-QINU