Difference between revisions of "Part:BBa K364315"

Latest revision as of 13:43, 25 October 2010

NHR-23 LBD

Nuclear hormone receptor family member 23.

The nhr-23 gene encodes a nuclear hormone receptor homolog that is required in all larval molts. NHR-23 is highly similar to Drosophila DHR3, an ecdysone-inducible gene product involved in metamorphosis. The NHR-23 protein is nuclear, and is present in all blastomeres during early embryogenesis. During later stages of morphogenesis, NHR-23 is restricted to epidermal cells. The expression of nhr-23 cycles between stages of larval development: during each intermolt period, levels of nhr-23 transcripts are 2-5 times greater than levels at each molt. Furthermore NHR-23 binds the DRS-type hormone response sequence in vitro.

Picture of gel electrophoresis: NHR 23 in pSB1C3 results a 495 bp long insert.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
INCOMPATIBLE WITH RFC[1000]
Illegal BsaI.rc site found at 76
Illegal BsaI.rc site found at 382
Illegal BsaI.rc site found at 466

@@ Line 2: / Line 2: @@
 <partinfo>BBa_K364315 short</partinfo>
-Nuclear hormone receptor family member nhr-23.
+Nuclear hormone receptor family member 23.
 The nhr-23 gene encodes a nuclear hormone receptor homolog that is required in all larval molts. NHR-23 is highly similar to Drosophila DHR3, an ecdysone-inducible gene product involved in metamorphosis.
-The NHR-23 protein is nuclear, and is present in all blastomeres during early embryogenesis; during later stages of morphogenesis, NHR-23 is restricted to epidermal cells.
+The NHR-23 protein is nuclear, and is present in all blastomeres during early embryogenesis. During later stages of morphogenesis, NHR-23 is restricted to epidermal cells.
-nhr-23 expression cycles between stages of larval development; during each intermolt period, levels of nhr-23 transcripts are 2-5 times greater than levels at each molt.
+The expression of nhr-23 cycles between stages of larval development: during each intermolt period, levels of nhr-23 transcripts are 2-5 times greater than levels at each molt.
-NHR-23 binds the DRS-type hormone response sequence in vitro.
+Furthermore NHR-23 binds the DRS-type hormone response sequence in vitro.
 [[Image:Team Debrecen pSB1C3-NHR23.jpg|800px|thumb|center|Picture of gel electrophoresis: NHR 23 in pSB1C3 results a 495 bp long insert.]]