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− | <partinfo>BBa_I10020 short</partinfo>
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− | This is the DNA enconding a sythetic construct of the Clostridium botulinum neurotoxin type A. (typically used in Botox injections)
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− | WARNING: Botulinum toxin type A is an extremely potent neurotoxin and can lead to widespread muscle paralysis and neuron damage. 200-300 pg/kg is a lethal dose for a human being. When using this part, gain permissin from the federal patent office and practice great caution with promoters and RBS sequences that may be put in a device with it (they should be chosen to limit expression of the protein to safe amounts with respect to the system the part is being inserted into).
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− | Further information can be found on PubMed via the reference: Shone, C.C., Quinn, C.P., Foster, K.A. (1997) Recombinant toxin fragments. Patent, PCT (W0/98/07864)-A 22-AUG-1997.
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− | <!-- Add more about the biology of this part here
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− | ===Usage and Biology===
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− | <span class='h3bb'>Sequence and Features</span>
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− | <partinfo>BBa_I10020 SequenceAndFeatures</partinfo>
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− | <!-- Uncomment this to enable Functional Parameter display
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− | ===Functional Parameters===
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− | <partinfo>BBa_I10020 parameters</partinfo>
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