Difference between revisions of "Part:BBa K314201:Experience"

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This experience page is provided so that any user may enter their experience using this part.<BR>Please enter
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how you used this part and how it worked out.
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===Evidence that Tsi2 works as expected===
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'''This evidence can be found on [http://2010.igem.org/Team:Washington/Gram_Negative/Test this page] from the 2010 UW iGEM Wiki, under the heading "Evidence that Tse2 and Tsi2 are Function As Expected"'''
  
 
===Applications of BBa_K314201===
 
===Applications of BBa_K314201===
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If [https://parts.igem.org/wiki/index.php?title=Part:BBa_K314200 Tse2] is combined with a functioning Type 6 secretion system and [https://parts.igem.org/wiki/index.php?title=Part:BBa_K314201 Tsi2],it results in a killing system that can be targeted to gram negative bacteria. This could be used in a probiotic application.
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Tsi2 is necessary for the generation of Gram-negative bacteria that have been directed to target other Gram-negative bacteria for killing by [https://parts.igem.org/Part:BBa_K314200 Tse2] in response to a user-defined signal.  Tsi2 is necessary because it protects host cells from death caused by the Tse2 toxic protein.
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If the antitoxin Tsi2 is combined with a functioning Type 6 Secretion System and the toxin [https://parts.igem.org/wiki/index.php?title=Part:BBa_K314200 Tse2] it results in a killing system that can be targeted to Gram-negative bacteria. This could be used in a probiotic application.  This was the goal behind the Gram-negative portion of the [http://2010.igem.org/Team:Washington 2010 UW iGEM project].
  
 
===User Reviews===
 
===User Reviews===

Latest revision as of 23:11, 21 October 2010


Evidence that Tsi2 works as expected

This evidence can be found on [http://2010.igem.org/Team:Washington/Gram_Negative/Test this page] from the 2010 UW iGEM Wiki, under the heading "Evidence that Tse2 and Tsi2 are Function As Expected"

Applications of BBa_K314201

Tsi2 is necessary for the generation of Gram-negative bacteria that have been directed to target other Gram-negative bacteria for killing by Tse2 in response to a user-defined signal. Tsi2 is necessary because it protects host cells from death caused by the Tse2 toxic protein.

If the antitoxin Tsi2 is combined with a functioning Type 6 Secretion System and the toxin Tse2 it results in a killing system that can be targeted to Gram-negative bacteria. This could be used in a probiotic application. This was the goal behind the Gram-negative portion of the [http://2010.igem.org/Team:Washington 2010 UW iGEM project].

User Reviews

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