Difference between revisions of "Part:BBa K5374000"

Latest revision as of 08:04, 16 September 2024

SPARC/OD. A collagen-binding domain involved in tissue repair and bone mineralization through ECM in

SPARC (Secreted Protein Acidic and Rich in Cysteine) binds to collagen, facilitating matrix remodeling and tissue repair, particularly in bone.

SPARC (Secreted Protein Acidic and Rich in Cysteine) and OD (Osteonectin Domain): This domain is involved in regulating the interaction between cells and the extracellular matrix (ECM), particularly binding to collagen and influencing matrix remodeling. It plays a role in tissue repair and bone mineralization.

Sequence and Features

Assembly Compatibility:

10
INCOMPATIBLE WITH RFC[10]
Illegal EcoRI site found at 484
12
INCOMPATIBLE WITH RFC[12]
Illegal EcoRI site found at 484
21
INCOMPATIBLE WITH RFC[21]
Illegal EcoRI site found at 484
Illegal BamHI site found at 288
23
INCOMPATIBLE WITH RFC[23]
Illegal EcoRI site found at 484
25
INCOMPATIBLE WITH RFC[25]
Illegal EcoRI site found at 484
1000
COMPATIBLE WITH RFC[1000]

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 <partinfo>BBa_K5374000 short</partinfo>
-SPARC (Secreted Protein Acidic and Rich in Cysteine), also known as osteonectin, is a matricellular protein that influences cell-matrix interactions and has a strong affinity for collagen. It plays a role in tissue remodeling and wound healing. SPARC binds to various types of collagen, particularly type I collagen, facilitating cellular adhesion and migration.
+SPARC (Secreted Protein Acidic and Rich in Cysteine) binds to collagen, facilitating matrix remodeling and tissue repair, particularly in bone.
+SPARC (Secreted Protein Acidic and Rich in Cysteine) and OD (Osteonectin Domain): This domain is involved in regulating the interaction between cells and the extracellular matrix (ECM), particularly binding to collagen and influencing matrix remodeling. It plays a role in tissue repair and bone mineralization.
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