Difference between revisions of "Part:BBa K4645023"
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__NOTOC__ | __NOTOC__ | ||
− | <partinfo> | + | ==<partinfo>BBa_K4645023 short</partinfo>== |
+ | MntA is the antitoxin of the toxin protein HepT. Together they form a toxin-antitoxin system. The HepT/MntA system belongs to type VII TA, where the antitoxin neutralizes the toxicity of the toxin not through direct interaction, but by post-translational modification of the toxin's active site. MntA can bind to HepT and polyadenylate HepT, thereby neutralizing the toxicity of HepT and reducing its RNase activity [1]. | ||
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===Sequence and Features=== | ===Sequence and Features=== | ||
<span class='h3bb'>Sequence and Features</span> | <span class='h3bb'>Sequence and Features</span> | ||
<partinfo>BBa_K3733009 SequenceAndFeatures</partinfo> | <partinfo>BBa_K3733009 SequenceAndFeatures</partinfo> | ||
− | + | ===Reference=== | |
− | + | <p>[1]Wang X, Yao J, Sun YC, Wood TK. Type VII Toxin/Antitoxin Classification System for Antitoxins that Enzymatically Neutralize Toxins. Trends Microbiol. 2021 May;29(5):388-393.</p> | |
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Latest revision as of 13:44, 12 October 2023
MntA (MNT-domain protein):An antitoxin
MntA is the antitoxin of the toxin protein HepT. Together they form a toxin-antitoxin system. The HepT/MntA system belongs to type VII TA, where the antitoxin neutralizes the toxicity of the toxin not through direct interaction, but by post-translational modification of the toxin's active site. MntA can bind to HepT and polyadenylate HepT, thereby neutralizing the toxicity of HepT and reducing its RNase activity [1].
Sequence and Features
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Reference
[1]Wang X, Yao J, Sun YC, Wood TK. Type VII Toxin/Antitoxin Classification System for Antitoxins that Enzymatically Neutralize Toxins. Trends Microbiol. 2021 May;29(5):388-393.