Difference between revisions of "Part:BBa K4165117"
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<partinfo>BBa_K4165117 short</partinfo> | <partinfo>BBa_K4165117 short</partinfo> | ||
| − | + | Part encodes for a synthetic peptide that binds to the PDZ domain of HTRA1 protein | |
===Usage and Biology=== | ===Usage and Biology=== | ||
| − | Synthetic peptide acquired by Phage display, Binds specifically to the water-sites of PDZ domain of HTRA1 Protein with IC<sub>50</sub> of 0.16 ± 0.01 and ΔG of 8.0 | + | Synthetic peptide acquired by Phage display, Binds specifically to the water-sites of PDZ domain of HTRA1 Protein with IC<sub>50</sub> of 0.16 ± 0.01 and ΔG of 8.0 kcal/mol |
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Latest revision as of 22:24, 11 October 2022
HTRA Binding Peptide 23
Part encodes for a synthetic peptide that binds to the PDZ domain of HTRA1 protein
Usage and Biology
Synthetic peptide acquired by Phage display, Binds specifically to the water-sites of PDZ domain of HTRA1 Protein with IC50 of 0.16 ± 0.01 and ΔG of 8.0 kcal/mol
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
References
Beuming, T., Farid, R., & Sherman, W. (2009). High‐energy water sites determine peptide binding affinity and specificity of PDZ domains. Protein Science, 18(8), 1609-1619.