Difference between revisions of "Part:BBa K4165118"
Salma Sobhy (Talk | contribs) |
|||
| (One intermediate revision by one other user not shown) | |||
| Line 3: | Line 3: | ||
<partinfo>BBa_K4165118 short</partinfo> | <partinfo>BBa_K4165118 short</partinfo> | ||
| − | + | Part encodes for a synthetic peptide that binds to the PDZ domain of HTRA1 protein | |
===Usage and Biology=== | ===Usage and Biology=== | ||
| − | Synthetic peptide acquired by Phage display, Binds specifically to the water-sites of PDZ domain of HTRA1 Protein with IC<sub>50</sub> of 0.41 ± 0.06 and ΔG of 21 | + | Synthetic peptide acquired by Phage display, Binds specifically to the water-sites of PDZ domain of HTRA1 Protein with IC<sub>50</sub> of 0.41 ± 0.06 and ΔG of 21 kcal/mol |
Latest revision as of 22:24, 11 October 2022
HTRA Binding Peptide 24
Part encodes for a synthetic peptide that binds to the PDZ domain of HTRA1 protein
Usage and Biology
Synthetic peptide acquired by Phage display, Binds specifically to the water-sites of PDZ domain of HTRA1 Protein with IC50 of 0.41 ± 0.06 and ΔG of 21 kcal/mol
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
References
Beuming, T., Farid, R., & Sherman, W. (2009). High‐energy water sites determine peptide binding affinity and specificity of PDZ domains. Protein Science, 18(8), 1609-1619.