Difference between revisions of "Part:BBa K4165236"
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− | 10 aa flexible linker | + | A 10 G and S aa flexible linker |
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+ | ===Dry Lab Characterization=== | ||
+ | In our project, we generated a library for GS flexible linkers to be tested on different parts of our system; each linker was modeled in the fusion protein, and we filtered through them until we found the suitable length to use in linking our PROTAC, clamps, and switches together. | ||
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+ | ===References=== | ||
+ | 1- Yuan, S., Chan, H. S., & Hu, Z. (2017). Using pymol as a platform for computational drug design. WIREs Computational Molecular Science, 7(2). doi:10.1002/wcms.1298 | ||
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===Functional Parameters=== | ===Functional Parameters=== | ||
<partinfo>BBa_K4165236 parameters</partinfo> | <partinfo>BBa_K4165236 parameters</partinfo> | ||
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Latest revision as of 08:52, 11 October 2022
GGSGGGGSGG
A 10 G and S aa flexible linker
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Dry Lab Characterization
In our project, we generated a library for GS flexible linkers to be tested on different parts of our system; each linker was modeled in the fusion protein, and we filtered through them until we found the suitable length to use in linking our PROTAC, clamps, and switches together.
References
1- Yuan, S., Chan, H. S., & Hu, Z. (2017). Using pymol as a platform for computational drug design. WIREs Computational Molecular Science, 7(2). doi:10.1002/wcms.1298