Difference between revisions of "Part:BBa K4256111"

 
 
(One intermediate revision by the same user not shown)
Line 1: Line 1:
  
 +
 +
__NOTOC__
 +
<partinfo>BBa_K4256111 short</partinfo>
 +
 +
It is a component of the CcdA/CcdB Type II Toxin-antitoxin (TA) system. It encodes the CcdA antidote, which can prevent CcdB toxicity by forming a tight CcdA-CcdB complex. As a model system, by ensuring an antidote-toxin ratio greater than one, this mechanism might prevent the harmful effect of CcdB in plasmid-containing bacteria. The CcdA-CcdB toxin-antitoxin system we used is a killing switch that is relatively nontoxic to human and other mammalian cells.
 +
 +
<!-- Add more about the biology of this part here
 +
===Usage and Biology===
 +
 +
<!-- -->
 +
<span class='h3bb'>Sequence and Features</span>
 +
<partinfo>BBa_K4256111 SequenceAndFeatures</partinfo>
 +
 +
 +
<!-- Uncomment this to enable Functional Parameter display
 +
===Functional Parameters===
 +
<partinfo>BBa_K4256111 parameters</partinfo>
 +
<!-- -->

Latest revision as of 16:19, 11 October 2022


ccdA

It is a component of the CcdA/CcdB Type II Toxin-antitoxin (TA) system. It encodes the CcdA antidote, which can prevent CcdB toxicity by forming a tight CcdA-CcdB complex. As a model system, by ensuring an antidote-toxin ratio greater than one, this mechanism might prevent the harmful effect of CcdB in plasmid-containing bacteria. The CcdA-CcdB toxin-antitoxin system we used is a killing switch that is relatively nontoxic to human and other mammalian cells.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]