Difference between revisions of "Part:BBa K3873333"
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<partinfo>BBa_K3873333 short</partinfo> | <partinfo>BBa_K3873333 short</partinfo> | ||
− | miRNA126a---a microRNA which can target the mRNA of DNA methyltransferase (DNMT) 3B, is coded to downregulate the expression of DNMTs. The inhibition of DNMTs in turn promotes the expression of FOXP3. | + | miRNA126a---a microRNA which can target the mRNA of DNA methyltransferase (DNMT) 3B, is coded to downregulate the expression of DNMTs. The inhibition of DNMTs in turn promotes the expression of FOXP3. And then the imbalance between Th17 and Treg can be restored.(Th17 down regulated) |
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<partinfo>BBa_K3873333 parameters</partinfo> | <partinfo>BBa_K3873333 parameters</partinfo> | ||
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Latest revision as of 02:08, 21 October 2021
mi126a
miRNA126a---a microRNA which can target the mRNA of DNA methyltransferase (DNMT) 3B, is coded to downregulate the expression of DNMTs. The inhibition of DNMTs in turn promotes the expression of FOXP3. And then the imbalance between Th17 and Treg can be restored.(Th17 down regulated)
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]