Difference between revisions of "Part:BBa K4040014"
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__NOTOC__ | __NOTOC__ | ||
<partinfo>BBa_K4040014 short</partinfo> | <partinfo>BBa_K4040014 short</partinfo> | ||
− | + | ===Sequence and Features=== | |
− | We used CD8a signal peptide to build the synthetic receptors. | + | <partinfo>BBa_K4040014 SequenceAndFeatures</partinfo> |
+ | We used the CD8a signal peptide to build the synthetic receptors. Synthetic receptors contained the human CD8a signal peptide followed by the scFv linked in-frame to the hinge domain of the CD8a molecule, transmembrane region of the human CD8 molecule, | ||
+ | and intracellular signaling domains of the FCER1G, MEGF10, MERTK or CD3z molecules. | ||
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===Usage and Biology=== | ===Usage and Biology=== | ||
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Latest revision as of 11:41, 4 October 2021
CD8a signal peptide
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
We used the CD8a signal peptide to build the synthetic receptors. Synthetic receptors contained the human CD8a signal peptide followed by the scFv linked in-frame to the hinge domain of the CD8a molecule, transmembrane region of the human CD8 molecule, and intracellular signaling domains of the FCER1G, MEGF10, MERTK or CD3z molecules.