Difference between revisions of "Part:BBa K3905003"

 
 
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Our Anti-miRNA has two halves: The first half of this RNA strand binds to half of miRNA hsa210-3p whilst the second half consists of multiple repeated Guanine bases. This creates a duplex with a trigger region of the anti-miRNA and the miRNA 210-3p. This trigger can turn BBA_K3905002 (gen1 210-3p Toehold Switch) into its 'on' state.
 
Our Anti-miRNA has two halves: The first half of this RNA strand binds to half of miRNA hsa210-3p whilst the second half consists of multiple repeated Guanine bases. This creates a duplex with a trigger region of the anti-miRNA and the miRNA 210-3p. This trigger can turn BBA_K3905002 (gen1 210-3p Toehold Switch) into its 'on' state.
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<img width="800px" src="https://2021.igem.org/wiki/images/thumb/d/de/T--City_of_London_UK--Antimirna.png/1200px-T--City_of_London_UK--Antimirna.png">
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Diagram of antiRNA and miRNA binding.
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Latest revision as of 16:12, 21 October 2021


gen1 210-3p Anti-miRNA

Our Anti-miRNA has two halves: The first half of this RNA strand binds to half of miRNA hsa210-3p whilst the second half consists of multiple repeated Guanine bases. This creates a duplex with a trigger region of the anti-miRNA and the miRNA 210-3p. This trigger can turn BBA_K3905002 (gen1 210-3p Toehold Switch) into its 'on' state.

Diagram of antiRNA and miRNA binding.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]