Difference between revisions of "Part:BBa K3132017"
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'''Summary''' | '''Summary''' | ||
| − | Interleukin-15 (IL-15) is a pleiotropic cytokine with variety of biological functions in many different cell types. It plays a major role in protective immune and inflammatory responses to microbial invaders and parasites. It is involved in modulating immune cells of both the innate and adaptive immune systems. IL-15 is a cytokine with potent survival and immunomodulatory effects on cells of both innate and adaptive immune systems. It has the ability to activate and expand NK cells, NKT cells, CD8+ effector memory and central memory T lymphocytes. | + | Interleukin-15 (IL-15) is a pleiotropic cytokine with variety of biological functions in many different cell types. It plays a major role in protective immune and inflammatory responses to microbial invaders and parasites. It is involved in modulating immune cells of both the innate and adaptive immune systems. IL-15 is a cytokine with potent survival and immunomodulatory effects on cells of both innate and adaptive immune systems. It has the ability to activate and expand NK cells, NKT cells, CD8+ effector memory and central memory T lymphocytes. |
==References== | ==References== | ||
1. Perera, P. Y., Lichy, J. H., Waldmann, T. A., & Perera, L. P. (2012). The role of interleukin-15 in inflammation and immune responses to infection: implications for its therapeutic use. Microbes and infection, 14(3), 247–261. https://doi.org/10.1016/j.micinf.2011.10.006 | 1. Perera, P. Y., Lichy, J. H., Waldmann, T. A., & Perera, L. P. (2012). The role of interleukin-15 in inflammation and immune responses to infection: implications for its therapeutic use. Microbes and infection, 14(3), 247–261. https://doi.org/10.1016/j.micinf.2011.10.006 | ||
Latest revision as of 17:58, 23 October 2020
human interleukine 15
In order to make the monitoring device has higher sensitivity,IL-15 proteins have high secretory capability. At the same time, to reduce the interference of IL-15 proteins original expression, we fused suntag which had been well characterized in this literature and another generic protein label flag to I-15 proteins, anticipating this device can detect IL-15-tag signal molecules secreted by the core device.
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000INCOMPATIBLE WITH RFC[1000]Illegal SapI.rc site found at 296
MIT_MAHE 2020
Summary
Interleukin-15 (IL-15) is a pleiotropic cytokine with variety of biological functions in many different cell types. It plays a major role in protective immune and inflammatory responses to microbial invaders and parasites. It is involved in modulating immune cells of both the innate and adaptive immune systems. IL-15 is a cytokine with potent survival and immunomodulatory effects on cells of both innate and adaptive immune systems. It has the ability to activate and expand NK cells, NKT cells, CD8+ effector memory and central memory T lymphocytes.
References
1. Perera, P. Y., Lichy, J. H., Waldmann, T. A., & Perera, L. P. (2012). The role of interleukin-15 in inflammation and immune responses to infection: implications for its therapeutic use. Microbes and infection, 14(3), 247–261. https://doi.org/10.1016/j.micinf.2011.10.006