Difference between revisions of "Part:BBa K3117028"
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__NOTOC__ | __NOTOC__ | ||
<partinfo>BBa_K3117028 short</partinfo> | <partinfo>BBa_K3117028 short</partinfo> | ||
− | The linker BBa_K3117028 consists of three repeats of four times | + | |
+ | The linker BBa_K3117028 consists of three repeats of four times Glycine and one time Serine. (Gly4Ser)3 linker is one of the most widely used flexible linker that can sustain the bioactivity of fusion proteins. It was used by 2019 FAU_Erlangen to create a bispecific antibody targeting GPA33 on colon cancer cells and CD3 on T cells. | ||
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Latest revision as of 01:54, 22 October 2019
((Glycine)x4-Serine Linker) x3
The linker BBa_K3117028 consists of three repeats of four times Glycine and one time Serine. (Gly4Ser)3 linker is one of the most widely used flexible linker that can sustain the bioactivity of fusion proteins. It was used by 2019 FAU_Erlangen to create a bispecific antibody targeting GPA33 on colon cancer cells and CD3 on T cells.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]