Difference between revisions of "Part:BBa K3110048"
 
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Interleukin 12 (IL-12) is an interleukin (a group of cytokines) that is naturally produced by dendritic cells, macrophages, neutrophils, and human B-lymphoblastoid cells which can be used to reduce the tumour size. Codon optimisation was done using Twist Codon optimisation tool.
 
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===Usage and Biology===
 
  
 
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<h1>Usage and Biology</h1>
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IL12 is an natural heterodimeric cytokine, composed of a disulfide-bound 35 kDa subunit (p35) and a 40 kDa subunit (p40) which enhances both innate and adaptative immune system. It is primarily produced by antigen-presenting cells such as dentritic cells, macrophage cells etc. which can be used to reduce the tumour size.

Latest revision as of 20:15, 21 October 2019


IL12 FLAG-tag (Codon Optimized)


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Usage and Biology

IL12 is an natural heterodimeric cytokine, composed of a disulfide-bound 35 kDa subunit (p35) and a 40 kDa subunit (p40) which enhances both innate and adaptative immune system. It is primarily produced by antigen-presenting cells such as dentritic cells, macrophage cells etc. which can be used to reduce the tumour size.