Difference between revisions of "Part:BBa K3102009"

Latest revision as of 15:17, 14 October 2019

GND (6-phosphogluconate dehydrogenase)

GND (6-phosphogluconate dehydrogenase) from Corynebacterium glutamicum catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2, with simultaneaous reduction of NAD+ to NADH in the pentose phosphate pathway. This part is used to increase flavin production.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
INCOMPATIBLE WITH RFC[25]
Illegal AgeI site found at 454
1000
INCOMPATIBLE WITH RFC[1000]
Illegal SapI.rc site found at 184

@@ Line 3: / Line 3: @@
 <partinfo>BBa_K3102009 short</partinfo>
-GND (6-phosphogluconate dehydrogenase) from Corynebacterium glutamicum catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2, with concomitant reduction of NADP to NADPH in the pentose phosphate pathway. This enzyme catalyzes the following reactions after ZWF and PGL genes.
+GND (6-phosphogluconate dehydrogenase) from Corynebacterium glutamicum catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2, with simultaneaous reduction of NAD+ to NADH in the pentose phosphate pathway.
-This part is useful to increase flavin production.
+This part is used to increase flavin production.
-"Conformational changes associated with cofactor/substrate binding of 6-phosphogluconate dehydrogenase from Escherichia coli and Klebsiella pneumoniae: Implications for enzyme mechanism." Chen Y.Y., Ko T.P., Chen W.H., Lo L.P., Lin C.H., Wang A.H. J. Struct. Biol. 169:25-35(2010)