Difference between revisions of "Part:BBa K2729010"
 
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<partinfo>BBa_K2729010 short</partinfo>
 
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==Usage and Biology==
 
Flavivirus Capsid (C), prM (precursor Membrane) and Envelope (E) are structural proteins responsible for gathering the viral RNA into a nucleocapsid that forms the core of a mature virus particle.
 
Flavivirus Capsid (C), prM (precursor Membrane) and Envelope (E) are structural proteins responsible for gathering the viral RNA into a nucleocapsid that forms the core of a mature virus particle.
  
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==Characterization==
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===Usage and Biology===
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The prM protein consists of an N-terminal pr domain followed by the M protein separated by a furin cleavage site.(15) The pr part of the protein consists mainly of β-strands, whereas the M portion consists of a linear structure followed by a mainly α-helical stem region and two transmembrane helices.
  
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==Sequence and Features==
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<span class='h3bb'>Sequence and Features</span>
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<partinfo>BBa_K2729010 SequenceAndFeatures</partinfo>
 
<partinfo>BBa_K2729010 SequenceAndFeatures</partinfo>
  
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==Reference==
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- [https://pubs.acs.org/doi/10.1021/bi500724k Membranotropic regions of the dengue virus prM protein]
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===Functional Parameters===
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<partinfo>BBa_K2729010 parameters</partinfo>
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==Characterization==
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The prM protein consists of an N-terminal pr domain followed by the M protein separated by a furin cleavage site.(15) The pr part of the protein consists mainly of β-strands, whereas the M portion consists of a linear structure followed by a mainly α-helical stem region and two transmembrane helices.
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==reference==
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- [https://pubs.acs.org/doi/10.1021/bi500724k 1: Nemésio H, Villalaín J. Membranotropic regions of the dengue virus prM
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protein. Biochemistry. 2014 Aug 19;53(32):5280-9. doi: 10.1021/bi500724k. Epub
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2014 Aug 6. PubMed PMID: 25076193.
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Latest revision as of 18:24, 16 October 2018


DENV1 ancC-prM-E (Dengue Virus Serotype I)

Usage and Biology

Flavivirus Capsid (C), prM (precursor Membrane) and Envelope (E) are structural proteins responsible for gathering the viral RNA into a nucleocapsid that forms the core of a mature virus particle.

Characterization

The prM protein consists of an N-terminal pr domain followed by the M protein separated by a furin cleavage site.(15) The pr part of the protein consists mainly of β-strands, whereas the M portion consists of a linear structure followed by a mainly α-helical stem region and two transmembrane helices.

Sequence and Features


Assembly Compatibility:
  • 10
    INCOMPATIBLE WITH RFC[10]
    Illegal SpeI site found at 1831
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal SpeI site found at 1831
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BglII site found at 1245
    Illegal BglII site found at 1856
  • 23
    INCOMPATIBLE WITH RFC[23]
    Illegal SpeI site found at 1831
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal SpeI site found at 1831
    Illegal AgeI site found at 1450
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal BsaI.rc site found at 217
    Illegal BsaI.rc site found at 367

Reference

- Membranotropic regions of the dengue virus prM protein