Difference between revisions of "Part:BBa K2486112"

Latest revision as of 04:17, 28 October 2017

Anti-malarial peptide (SM1)2

[theoretical part] [not assembled, not synthesized, not sent, not characterized]

Anti malarial peptide that binds to the luminal side of the midgut epithelium of Anopheles mosquitos. (1) Used in paratransgenic approaches to block Plasmoidum transmission. (2)

1- Ghosh, Anil K., Paulo EM Ribolla, and Marcelo Jacobs-Lorena. "Targeting Plasmodium ligands on mosquito salivary glands and midgut with a phage display peptide library." Proceedings of the National Academy of Sciences 98.23 (2001): 13278-13281. APA

2 - Wang, Sibao, et al. "Driving mosquito refractoriness to Plasmodium falciparum with engineered symbiotic bacteria." Science 357.6358 (2017): 1399-1402.

Sequence codon optized to E. coli with https://www.idtdna.com/CodonOpt

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
COMPATIBLE WITH RFC[1000]

@@ Line 3: / Line 3: @@
 <partinfo>BBa_K2486112 short</partinfo>
-.
+[theoretical part] [not assembled, not synthesized, not sent, not characterized]
+Anti malarial peptide that binds to the luminal side of the midgut epithelium of ''Anopheles'' mosquitos. (1)
+Used in paratransgenic approaches to block ''Plasmoidum'' transmission. (2)
+-  Ghosh, Anil K., Paulo EM Ribolla, and Marcelo Jacobs-Lorena. "Targeting Plasmodium ligands on mosquito salivary glands and midgut with a phage display peptide library." Proceedings of the National Academy of Sciences 98.23 (2001): 13278-13281.
+APA
+- Wang, Sibao, et al. "Driving mosquito refractoriness to Plasmodium falciparum with engineered symbiotic bacteria." Science 357.6358 (2017): 1399-1402.
+Sequence codon optized to E. coli with https://www.idtdna.com/CodonOpt
 <!-- Add more about the biology of this part here