Difference between revisions of "Part:BBa K2309000"

Latest revision as of 09:52, 26 September 2017

AIP receptor

AgrC is a membrane-located protein, which can sense specifically mature group 1 autoinducing peptides (also known as AIPs, a kind of intracellular signal molecule) that are synthesized by Staphylococcus. When bound by AIPs, it then will change the conformation and gain the capability to phosphorylate protein AgrA, which can futher activate P2 promotor expression.

Wrong use of this group one agr regulation may lead to adverse experimental consequences. Appliction of AIP-II and AIP-IV into this sensing system will cause inhibition of the agr-regulated expression.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
COMPATIBLE WITH RFC[1000]

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 <partinfo>BBa_K2309000 short</partinfo>
-AgrC is a membrane-located protein, which can sense mature autoinducing peptides (also known as AIPs a kind of intracellular signal molecule) that are synthesized by Staphylococcus. When bound by AIPs, it then will change the conformation and gain the capability to phosphorylate protein AgrA, which can futher activate P2 promotor expression.
+AgrC is a membrane-located protein, which can sense specifically mature group 1 autoinducing peptides (also known as AIPs, a kind of intracellular signal molecule) that are synthesized by Staphylococcus. When bound by AIPs, it then will change the conformation and gain the capability to phosphorylate protein AgrA, which can futher activate P2 promotor expression.
+Wrong use of this group one agr regulation may lead to adverse experimental consequences. Appliction of AIP-II and AIP-IV into this sensing system will cause inhibition of the agr-regulated expression.
 <!-- Add more about the biology of this part here