Difference between revisions of "Part:BBa K1391106:Experience"

Latest revision as of 23:04, 1 November 2014

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Applications of BBa_K1391106

Spleen Tyrosine Kinase (Syk) is a tyrosine kinase that has a high affinity for the phosphorylated immunoreceptor tyrosine-based activation motif (ITAM) of the CD79A and CD79B proteins (components of the B-Cell Receptor Complex). Syk binds to the phosphorylated ITAM and the ITAM then phosphorylates Syk allowing Syk to initiate a downstream signalling cascade that ordinarily results in the proliferation of B-Cells during clonal selection. This part is under an inducible TRE promoter that requires the presence of both the activator rtTA and the antibiotic Doxycycline for transcription to occur.

User Reviews

UNIQeece1c06a568abbc-partinfo-00000000-QINU UNIQeece1c06a568abbc-partinfo-00000001-QINU

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 This experience page is provided so that any user may enter their experience using this part.<BR>Please enter
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 ===Applications of BBa_K1391106===
+Spleen Tyrosine Kinase (Syk) is a tyrosine kinase that has a high affinity for the phosphorylated immunoreceptor tyrosine-based activation motif (ITAM) of the CD79A and CD79B proteins (components of the B-Cell Receptor Complex). Syk binds to the phosphorylated ITAM and the ITAM then phosphorylates Syk allowing Syk to initiate a downstream signalling cascade that ordinarily results in the proliferation of B-Cells during clonal selection.
 This part is under an inducible TRE promoter that requires the presence of both the activator rtTA and the antibiotic Doxycycline for transcription to occur.