Difference between revisions of "Part:BBa K861051"

Latest revision as of 14:56, 22 September 2012

FadR with a RBS and a terminator

FadR is a transcription regulator, which, when not binds to acyl-CoA can either serve as an activator for fatty acid synthesis gene like FabA, FabB and etc. or a repressor for fatty acid degradation gene like FadA, FadB, FadD and etc. After long chain fatty acid is converted into fatty acyl- CoA by FadD, it can bind to FadR. This binding will alter the conformation of FadR, making it unable to bind to the DNA sequence it recognizes. To our knowledge, there is no promoter exists in nature that can respond solely to FadR since those promoters are often regulated by glucose concentration or oxidative stress and many other factors.

This part contains a RBS and a terminator.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
COMPATIBLE WITH RFC[1000]

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-FadR is a transcription regulator, which, when not binds to acyl-CoA can either serve as an activator for fatty acid synthetase gene like FabA, FabB and etc. or a repressor for fatty acid degradation gene like FadA, FadB, FadD and etc. After long chain fatty acid is converted to fatty acyl- CoA by FadD, it can bind to FadR. This binding will alter the conformation of FadR, making it unable to bind to the DNA sequence it recognizes. To our knowledge, there is no promoter exists in nature that can respond solely to FadR since those promoters are often regulated by glucose concentration or oxidative stress and many other factors.
+FadR is a transcription regulator, which, when not binds to acyl-CoA can either serve as an activator for fatty acid synthesis gene like FabA, FabB and etc. or a repressor for fatty acid degradation gene like FadA, FadB, FadD and etc. After long chain fatty acid is converted into fatty acyl- CoA by FadD, it can bind to FadR. This binding will alter the conformation of FadR, making it unable to bind to the DNA sequence it recognizes. To our knowledge, there is no promoter exists in nature that can respond solely to FadR since those promoters are often regulated by glucose concentration or oxidative stress and many other factors.
-This device contains a RBS and a terminator.
+This part contains a RBS and a terminator.
 <!-- Add more about the biology of this part here