Difference between revisions of "Part:BBa K639002:Experience"

 
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===Applications of BBa_K639002===
 
===Applications of BBa_K639002===
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Previous studies have shown that the rrnB P1 promoter is downregulated by ppGpp [1], which is an alarmone involved in the stringent response in bacteria. Our project involved using the rrnB P1 promoter as a stress-sensor, where it would stop expressing an inhibitor for a second promoter, thus giving a signal.
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[1] Magnusson, Lisa U., Farewell, Anne, Nyström, Thomas: "ppGpp: a global regulator in Escherichia Coli", 2005
  
 
===User Reviews===
 
===User Reviews===

Latest revision as of 08:57, 26 August 2011

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Applications of BBa_K639002

Previous studies have shown that the rrnB P1 promoter is downregulated by ppGpp [1], which is an alarmone involved in the stringent response in bacteria. Our project involved using the rrnB P1 promoter as a stress-sensor, where it would stop expressing an inhibitor for a second promoter, thus giving a signal.


[1] Magnusson, Lisa U., Farewell, Anne, Nyström, Thomas: "ppGpp: a global regulator in Escherichia Coli", 2005

User Reviews

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