Difference between revisions of "Part:BBa K346088"
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__NOTOC__ | __NOTOC__ | ||
<partinfo>BBa_K346088 short</partinfo> | <partinfo>BBa_K346088 short</partinfo> | ||
This part is constructed for the expression of merC. MerC can transport Hg(II) into the cytosol without the help of merP. | This part is constructed for the expression of merC. MerC can transport Hg(II) into the cytosol without the help of merP. | ||
+ | For a long time, merC is considered to be of no use in the resistance to Hg(II) because mutations that affect the expression of MerC did not affect the resistance. The discovery in Thipobacillus isolated from mercury mines of operons that apparently had only merC and no merT genes forced reconsideration of the view that merC is vestigal. | ||
+ | It has been proposed that merC may be needed under conditions of very high Hg (II) exprosure, perhaps because merC system can uptake (Hg (II) without the need of merP. | ||
<!-- Add more about the biology of this part here | <!-- Add more about the biology of this part here |
Revision as of 01:43, 23 October 2010
RBS(BBa_B0034)+MerC
This part is constructed for the expression of merC. MerC can transport Hg(II) into the cytosol without the help of merP. For a long time, merC is considered to be of no use in the resistance to Hg(II) because mutations that affect the expression of MerC did not affect the resistance. The discovery in Thipobacillus isolated from mercury mines of operons that apparently had only merC and no merT genes forced reconsideration of the view that merC is vestigal. It has been proposed that merC may be needed under conditions of very high Hg (II) exprosure, perhaps because merC system can uptake (Hg (II) without the need of merP.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal NgoMIV site found at 384
- 1000COMPATIBLE WITH RFC[1000]