Difference between revisions of "Part:BBa K314202:Experience"
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===Evidence that Tsi2 works as expected===
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===Evidence that Tse2 and Tsi2 work as expected===
  
 
'''This evidence can be found on [http://2010.igem.org/Team:Washington/Gram_Negative/Test this page] from the 2010 UW iGEM Wiki, under the heading "Evidence that Tse2 and Tsi2 are Function As Expected"'''
 
'''This evidence can be found on [http://2010.igem.org/Team:Washington/Gram_Negative/Test this page] from the 2010 UW iGEM Wiki, under the heading "Evidence that Tse2 and Tsi2 are Function As Expected"'''
  
 
===Applications of BBa_K314202===
 
===Applications of BBa_K314202===
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The Tse2/Tsi2 locus could be used in conjunction with a functioning T6 secretion system to produce a gram negative bacterial killing system. Different promoters could be used for the locus to tune toxin production to different signals.
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Tse2 and Tsi2 locus can be combined with the Type 6 Secretion System to result in a bacterium that targets other Gram-negative bacteria for killing. By placing your own regulation upstream of the Tse2Tsi2 locus, you can induce toxin expression whenever you like in order to control bacteria-bacteria killing.
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This idea was used as a probiotic application (turning on the toxin in response to the detection of potentially pathogenic Gram-negative bacteria).  This was the goal behind the Gram-negative portion of the [http://2010.igem.org/Team:Washington 2010 UW iGEM project].
  
 
===User Reviews===
 
===User Reviews===

Latest revision as of 23:21, 21 October 2010

Evidence that Tse2 and Tsi2 work as expected

This evidence can be found on [http://2010.igem.org/Team:Washington/Gram_Negative/Test this page] from the 2010 UW iGEM Wiki, under the heading "Evidence that Tse2 and Tsi2 are Function As Expected"

Applications of BBa_K314202

Tse2 and Tsi2 locus can be combined with the Type 6 Secretion System to result in a bacterium that targets other Gram-negative bacteria for killing. By placing your own regulation upstream of the Tse2Tsi2 locus, you can induce toxin expression whenever you like in order to control bacteria-bacteria killing.

This idea was used as a probiotic application (turning on the toxin in response to the detection of potentially pathogenic Gram-negative bacteria). This was the goal behind the Gram-negative portion of the [http://2010.igem.org/Team:Washington 2010 UW iGEM project].

User Reviews

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