Difference between revisions of "Part:BBa K314201:Experience"
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| − | + | ===Evidence that Tsi2 works as expected=== | |
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| + | '''This evidence can be found on [http://2010.igem.org/Team:Washington/Gram_Negative/Test this page] from the 2010 UW iGEM Wiki, under the heading "Evidence that Tse2 and Tsi2 are Function As Expected"''' | ||
===Applications of BBa_K314201=== | ===Applications of BBa_K314201=== | ||
Latest revision as of 23:11, 21 October 2010
Evidence that Tsi2 works as expected
This evidence can be found on [http://2010.igem.org/Team:Washington/Gram_Negative/Test this page] from the 2010 UW iGEM Wiki, under the heading "Evidence that Tse2 and Tsi2 are Function As Expected"
Applications of BBa_K314201
Tsi2 is necessary for the generation of Gram-negative bacteria that have been directed to target other Gram-negative bacteria for killing by Tse2 in response to a user-defined signal. Tsi2 is necessary because it protects host cells from death caused by the Tse2 toxic protein.
If the antitoxin Tsi2 is combined with a functioning Type 6 Secretion System and the toxin Tse2 it results in a killing system that can be targeted to Gram-negative bacteria. This could be used in a probiotic application. This was the goal behind the Gram-negative portion of the [http://2010.igem.org/Team:Washington 2010 UW iGEM project].
User Reviews
UNIQ857e3f3ed39a924e-partinfo-00000000-QINU UNIQ857e3f3ed39a924e-partinfo-00000001-QINU