Difference between revisions of "Part:BBa K364301"

 
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induce mitochondrial dysfunction and caspase activation. PUMA ablation or inhibition leads to
 
induce mitochondrial dysfunction and caspase activation. PUMA ablation or inhibition leads to
 
apoptosis deficiency underlying increased risks for cancer development and therapeutic resistance.
 
apoptosis deficiency underlying increased risks for cancer development and therapeutic resistance.
  Therefore, PUMA is a general sensor of cell death stimuli and a promising drug target for cancer therapy and tissue damage.
+
   
  
 
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Latest revision as of 10:15, 13 August 2010

hPUMA

PUMA

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]