Difference between revisions of "Part:BBa K137112"

 
 
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lamB is the a porin protein which is part of the maltose pathway. It is also the receptor associated and required fro lambda phage infection.
 
lamB is the a porin protein which is part of the maltose pathway. It is also the receptor associated and required fro lambda phage infection.
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===CUHK-HongKong-SBS 2024===
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Maltoporin, also known as the LamB protein, is a malto-oligosaccharide-selective pore protein located in the outer membrane of Escherichia coli, playing a crucial role in the transport of maltose and maltodextrins (1). It is vital for the translocation of maltodextrins that consist of more than three glucosyl units linked by alpha 1-4 bonds. The protein features a hydrophobic pathway, commonly described as a 'greasy slide,' composed of aromatic residues that assist in the guidance and selection of sugars during their passage through the channel. Furthermore, maltoporin serves as a receptor for several bacteriophages, including lambda (2).
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===References===
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1. Heine, H.-G., Kyngdon, J., & Ferenci, T. (1987). Sequence determinants in the lamB gene of Escherichia coli influencing the binding and pore selectivity of maltoporin. Gene, 53(2-3), 287–292. https://doi.org/10.1016/0378-1119(87)90018-7
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2. UniProt. (2024b). P02943 · LAMB_ECOLI. Uniprot.org. https://www.uniprot.org/uniprotkb/P02943/entry
  
 
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Latest revision as of 19:22, 25 September 2024


lamB

lamB is the a porin protein which is part of the maltose pathway. It is also the receptor associated and required fro lambda phage infection.

CUHK-HongKong-SBS 2024

Maltoporin, also known as the LamB protein, is a malto-oligosaccharide-selective pore protein located in the outer membrane of Escherichia coli, playing a crucial role in the transport of maltose and maltodextrins (1). It is vital for the translocation of maltodextrins that consist of more than three glucosyl units linked by alpha 1-4 bonds. The protein features a hydrophobic pathway, commonly described as a 'greasy slide,' composed of aromatic residues that assist in the guidance and selection of sugars during their passage through the channel. Furthermore, maltoporin serves as a receptor for several bacteriophages, including lambda (2).

References

1. Heine, H.-G., Kyngdon, J., & Ferenci, T. (1987). Sequence determinants in the lamB gene of Escherichia coli influencing the binding and pore selectivity of maltoporin. Gene, 53(2-3), 287–292. https://doi.org/10.1016/0378-1119(87)90018-7

2. UniProt. (2024b). P02943 · LAMB_ECOLI. Uniprot.org. https://www.uniprot.org/uniprotkb/P02943/entry

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal AgeI site found at 151
    Illegal AgeI site found at 1212
  • 1000
    COMPATIBLE WITH RFC[1000]