Difference between revisions of "Part:BBa K243028"
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== pMA FOS-Split Linker-Fok_a == | == pMA FOS-Split Linker-Fok_a == | ||
| − | Activator protein-1 (AP-1) is a crucial transcription factor implicated in numerous cancers. | + | Activator protein-1 (AP-1) is a crucial transcription factor implicated in numerous cancers. Nine homologues of the AP-1 leucine zipper region have been characterized. Via leucin zipper they interact among each other and with their bipartite domain they bind DNA. (Abate et al., Mol Cell Biol. 1991 July). |
| − | [[Image:1fos bio r 250.jpg]] | + | [[Image:1fos bio r 250.jpg]]Heterodimeric Fos complex (http://www.rcsb.org/pdb/explore/images.do?structureId=1FOS) |
===Usage and Biology=== | ===Usage and Biology=== | ||
Revision as of 22:45, 20 October 2009
pMA FOS-Split Linker-Fok_a
Activator protein-1 (AP-1) is a crucial transcription factor implicated in numerous cancers. Nine homologues of the AP-1 leucine zipper region have been characterized. Via leucin zipper they interact among each other and with their bipartite domain they bind DNA. (Abate et al., Mol Cell Biol. 1991 July).
Heterodimeric Fos complex (http://www.rcsb.org/pdb/explore/images.do?structureId=1FOS)