Difference between revisions of "Part:BBa K4825000"
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By accumulating MVA through the over expression of tHMG1, MVA pathway is expressed more efficiently, and the yield of isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP) would increase, which are both precursors of pinene, hence the yield of pinene can be increased. " | By accumulating MVA through the over expression of tHMG1, MVA pathway is expressed more efficiently, and the yield of isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP) would increase, which are both precursors of pinene, hence the yield of pinene can be increased. " | ||
− | + | Add more about the biology of this part here | |
===Usage and Biology=== | ===Usage and Biology=== | ||
Revision as of 18:09, 11 October 2023
tHMG1
"HMG1, 3-hydroxy-3-methylglutaryl-CoA reductase, is the endogenous gene in yeast. It can catalyze the conversion from hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonate (MVA). By accumulating MVA through the over expression of tHMG1, MVA pathway is expressed more efficiently, and the yield of isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP) would increase, which are both precursors of pinene, hence the yield of pinene can be increased. "
Add more about the biology of this part here
Usage and Biology
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal NgoMIV site found at 1456
- 1000COMPATIBLE WITH RFC[1000]