Difference between revisions of "Part:BBa K4989003"

 
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==<strong>Butyrylo-CoA dehydrogenase <i>(bcd)</i></strong>==
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<html>It is an improved basic part of: <h5 style="color:ltblue;"><a href="https://parts.igem.org/Part:BBa_K1618043">BBa_K1618043</a> of iGEM 2015 NRP-UEA-Norwich.
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<h5 style="color:ltblue;">
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</html>
  
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==<strong>Alternative names of the enzyme</strong>==
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Other names that the butyryl-CoA dehydrogease enzyme could be found in the bibliography are:
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<br>
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Systematic name: short-chain acyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase
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<br>
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Else: short-chain acyl-CoA dehydrogenase, <br>butyryl-CoA dehydrogenase, <br>butanoyl-CoA dehydrogenase,
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<br>butyryl dehydrogenase, <br>unsaturated acyl-CoA reductase, <br>ethylene reductase, <br>enoyl-coenzyme A reductase,
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unsaturated acyl coenzyme A reductase, <br>butyryl coenzyme A dehydrogenase, <br>short-chain acyl CoA dehydrogenase,
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short-chain acyl-coenzyme A dehydrogenase, <br>3-hydroxyacyl CoA reductase, <br>butanoyl-CoA:(acceptor) 2,3-oxidoreductase,
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ACADS (gene name)
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==<strong>Application in the field of biology</strong>==
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The <i>bcd</i> gene encodes for a flavoprotein oxidoreductase that has great specificity for short-chain fatty acids: <b>butyryl-CoA dehydrogenase</b>. The enzyme catalyzes the a and b desaturation of acyl-CoA substrates[1]. This enzyme doesn’t utilize NAD(H) directly but requires electron transfer flavoproteins to form a complex and transfer electrons from butyryl-CoA dehydrogenase to NAD(H)[2].
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<br>
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The full reaction is shown below:
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<br>
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2 NADH+2Fdox + crotonyl−CoA↔2 NAD+2 Fdred+ butyryl−CoA
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[[File:1buc.png|none|frame|700px|]]

Revision as of 14:25, 8 October 2023

Butyrylo-CoA dehydrogenase (bcd)

It is an improved basic part of:

BBa_K1618043 of iGEM 2015 NRP-UEA-Norwich.


Alternative names of the enzyme

Other names that the butyryl-CoA dehydrogease enzyme could be found in the bibliography are:
Systematic name: short-chain acyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase
Else: short-chain acyl-CoA dehydrogenase,
butyryl-CoA dehydrogenase,
butanoyl-CoA dehydrogenase,
butyryl dehydrogenase,
unsaturated acyl-CoA reductase,
ethylene reductase,
enoyl-coenzyme A reductase, unsaturated acyl coenzyme A reductase,
butyryl coenzyme A dehydrogenase,
short-chain acyl CoA dehydrogenase, short-chain acyl-coenzyme A dehydrogenase,
3-hydroxyacyl CoA reductase,
butanoyl-CoA:(acceptor) 2,3-oxidoreductase, ACADS (gene name)


Application in the field of biology

The bcd gene encodes for a flavoprotein oxidoreductase that has great specificity for short-chain fatty acids: butyryl-CoA dehydrogenase. The enzyme catalyzes the a and b desaturation of acyl-CoA substrates[1]. This enzyme doesn’t utilize NAD(H) directly but requires electron transfer flavoproteins to form a complex and transfer electrons from butyryl-CoA dehydrogenase to NAD(H)[2].
The full reaction is shown below:
2 NADH+2Fdox + crotonyl−CoA↔2 NAD+2 Fdred+ butyryl−CoA

File:1buc.png