Difference between revisions of "Part:BBa K4586015"

Revision as of 12:56, 21 September 2023

L7Ae

Part Description

L7Ae is a 50S ribosomal protein that is considered an RNA-binding protein. It has the ability to recognize its K-turn motif or C/D box in ribosomal RNA and can be used to build more complicated genetic circuits that are regulated at both the translational and transcriptional levels as well as as an adapter for RNA binding in the extracellular vesicles.

Usage

Our team uses this part in loading our cargo into the exosomes. By binding to the C/D boxes to load a specific RNA into the vesicles, we fused it to RNA-motifs, which are bound specifically by RNA-binding proteins. Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
COMPATIBLE WITH RFC[1000]

@@ Line 7: / Line 7: @@
 ==Usage==
-By binding to the C-D boxes, a guide RNA, L7Ae, which is conjugated with CD63, aids in loading our cargo into the exosomes.
+Our team uses this part in loading our cargo into the exosomes. By binding to the C/D boxes to load a specific RNA into the vesicles, we fused it to RNA-motifs, which are bound specifically by RNA-binding proteins.
 <!-- Add more about the biology of this part here
 ===Usage and Biology===