Difference between revisions of "Part:BBa K4586006"
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<partinfo>BBa_K4586006 short</partinfo> | <partinfo>BBa_K4586006 short</partinfo> | ||
| − | It is a fragment of RNA that serves as a roadmap for enzymes that target RNA or DNA and builds complexes with them. These enzymes frequently remove, insert, or otherwise change the targeted RNA or DNA. | + | ==Part Description== |
| − | + | It is a fragment of RNA that serves as a roadmap for Cas enzymes that target RNA or DNA and builds complexes with them. These enzymes frequently remove, insert, or otherwise change the targeted RNA or DNA. | |
| − | + | ==Usage== | |
| + | Our guide RNA is designed to drive the activity of the Cas12k protein toward the target gene, which is the B-cell activating factor receptor (BAFF-R) gene, as knocking down this gene will affect the survival of the autoreactive B-cells and limit its pathogenic effect in RA | ||
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Revision as of 09:37, 20 September 2023
Guide RNA
Part Description
It is a fragment of RNA that serves as a roadmap for Cas enzymes that target RNA or DNA and builds complexes with them. These enzymes frequently remove, insert, or otherwise change the targeted RNA or DNA.
Usage
Our guide RNA is designed to drive the activity of the Cas12k protein toward the target gene, which is the B-cell activating factor receptor (BAFF-R) gene, as knocking down this gene will affect the survival of the autoreactive B-cells and limit its pathogenic effect in RA
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]