Difference between revisions of "Part:BBa K4656001"
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<partinfo>BBa_K4656001 short</partinfo>
 
<partinfo>BBa_K4656001 short</partinfo>
  
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Tdc can remove the carboxyl group from 5-hydroxytryptophan (5-HTP) and convert it into serotonin (5-hydroxytryptophan, 5-HT) . Tryptophan decarboxylase exists widely in animals and plants, especially in the central nervous system and gastrointestinal tract. 5-HTP is a precursor substance of neurotransmitter, while serotonin is an important neurotransmitter, similar to intestinal motor in terms of intestinal physiological function, and plays an important role in alleviating chronic constipation.  
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Tdc can remove the carboxyl group from 5-hydroxytryptophan (5-HTP) and convert it into serotonin (5-hydroxytryptophan, 5-HT). Tryptophan decarboxylase exists widely in animals and plants, especially in the central nervous system and gastrointestinal tract. 5-HTP is a precursor substance of neurotransmitter 5-HT, which is an important neurotransmitter, serving as intestinal motor in terms of intestinal physiological function, and plays a vital role in alleviating chronic constipation.  
  
 
===Usage and Biology===
 
===Usage and Biology===
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In our project, tdc and tph together catalyze the generation of 5-HT，when sensing a decrease in butyrate concentration.
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In our project, tdc and tph together catalyze the generation of 5-HT， when sensing a decrease in butyrate concentration.
  
 
===Sequence and Features===
 
===Sequence and Features===

Revision as of 15:43, 10 September 2023


TDC

Tdc can remove the carboxyl group from 5-hydroxytryptophan (5-HTP) and convert it into serotonin (5-hydroxytryptophan, 5-HT). Tryptophan decarboxylase exists widely in animals and plants, especially in the central nervous system and gastrointestinal tract. 5-HTP is a precursor substance of neurotransmitter 5-HT, which is an important neurotransmitter, serving as intestinal motor in terms of intestinal physiological function, and plays a vital role in alleviating chronic constipation.

Usage and Biology

In our project, tdc and tph together catalyze the generation of 5-HT， when sensing a decrease in butyrate concentration.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BglII site found at 1248
    Illegal BamHI site found at 732
    Illegal BamHI site found at 834
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal NgoMIV site found at 340
    Illegal NgoMIV site found at 775
    Illegal NgoMIV site found at 1330
    Illegal AgeI site found at 478
    Illegal AgeI site found at 1402
  • 1000
    COMPATIBLE WITH RFC[1000]