Difference between revisions of "Part:BBa K4201007"

 
 
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<partinfo>BBa_K4201007 short</partinfo>
 
<partinfo>BBa_K4201007 short</partinfo>
  
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Description
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The Taxane 5α-hydroxylase (T5αOH) naturally occuring in Yew trees metabolizes Taxadiene, the precursor molecule to Paclitaxel, into Taxadiene-5α-ol<sup>1</sup>. T5αOH is the second step in the synthesis pathway of paclitaxel<sup>1</sup>. Successful integration of this enzyme could help further the progress of the biosynthesis of paclitaxel.
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<!-- Add more about the biology of this part here

Latest revision as of 23:29, 11 October 2022


T5αOH

The Taxane 5α-hydroxylase (T5αOH) naturally occuring in Yew trees metabolizes Taxadiene, the precursor molecule to Paclitaxel, into Taxadiene-5α-ol1. T5αOH is the second step in the synthesis pathway of paclitaxel1. Successful integration of this enzyme could help further the progress of the biosynthesis of paclitaxel.


Sequence and Features


Assembly Compatibility:
  • 10
    INCOMPATIBLE WITH RFC[10]
    Illegal EcoRI site found at 184
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal EcoRI site found at 184
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal EcoRI site found at 184
    Illegal BglII site found at 800
  • 23
    INCOMPATIBLE WITH RFC[23]
    Illegal EcoRI site found at 184
  • 25
    INCOMPATIBLE WITH RFC[25]
    Unknown
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal BsaI site found at 1
    Illegal BsaI.rc site found at 1517