Difference between revisions of "Part:BBa K4165118"

Latest revision as of 22:24, 11 October 2022

HTRA Binding Peptide 24

Part encodes for a synthetic peptide that binds to the PDZ domain of HTRA1 protein

Usage and Biology

Synthetic peptide acquired by Phage display, Binds specifically to the water-sites of PDZ domain of HTRA1 Protein with IC₅₀ of 0.41 ± 0.06 and ΔG of 21 kcal/mol

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
COMPATIBLE WITH RFC[1000]

References

Beuming, T., Farid, R., & Sherman, W. (2009). High‐energy water sites determine peptide binding affinity and specificity of PDZ domains. Protein Science, 18(8), 1609-1619.

@@ Line 3: / Line 3: @@
 <partinfo>BBa_K4165118 short</partinfo>
-part encodes for a synthetic peptide that binds to the PDZ domain of HTRA1 protein
+Part encodes for a synthetic peptide that binds to the PDZ domain of HTRA1 protein
+===Usage and Biology===
+Synthetic peptide acquired by Phage display, Binds specifically to the water-sites of PDZ domain of HTRA1 Protein with IC<sub>50</sub> of 0.41 ± 0.06 and ΔG of 21 kcal/mol
-<!-- Add more about the biology of this part here
-===Usage and Biology===
 <!-- -->
-<span class='h3bb'>Sequence and Features</span>
+===<span class='h3bb'>Sequence and Features</span>===
 <partinfo>BBa_K4165118 SequenceAndFeatures</partinfo>
+===References===
+Beuming, T., Farid, R., & Sherman, W. (2009). High‐energy water sites determine peptide binding affinity and specificity of PDZ domains. Protein Science, 18(8), 1609-1619.
-<!-- Uncomment this to enable Functional Parameter display
-===Functional Parameters===
 <partinfo>BBa_K4165118 parameters</partinfo>
 <!-- -->