Difference between revisions of "Part:BBa K4165188"
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<partinfo>BBa_K4165188 SequenceAndFeatures</partinfo> | <partinfo>BBa_K4165188 SequenceAndFeatures</partinfo> | ||
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+ | ===Dry Lab Characterization=== | ||
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+ | <p style=" font-weight: bold; font-size:14px;"> Modeling </p> | ||
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+ | The peptide was modeled by several software (Alphafold-Apptest-Pepfold) and the best model from Alphafold scored 3 out of 6 according to our Quality assessment code. | ||
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+ | <html> | ||
+ | <p><img src="https://static.igem.wiki/teams/4165/wiki/parts-registry/mix.png" style="margin-left:200px;" alt="" width="500" /></p> | ||
+ | </html> | ||
+ | |||
+ | Figure 1. The 3D structure of peptide AB(39-42)-CLPFFD modeled by Alphafold | ||
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Latest revision as of 19:24, 11 October 2022
Amyloid beta peptide 8
This part encodes two Amyloid 𝛽 peptides (BBa_K4165186) and (BBa_K4165187) conjugated together. It has the ability to bind to A𝛽 plaques inside the brain.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Dry Lab Characterization
Modeling
The peptide was modeled by several software (Alphafold-Apptest-Pepfold) and the best model from Alphafold scored 3 out of 6 according to our Quality assessment code.
Figure 1. The 3D structure of peptide AB(39-42)-CLPFFD modeled by Alphafold