Difference between revisions of "Part:BBa K4461006"
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hchA performs a protective function under a wide range of stress conditions, and hchA null mutants exhibit a decreased ability to survive in deep stationary phase relative to hchA+ cells. Therefore, we believe it can be a strong indicator of the stationary phase. | hchA performs a protective function under a wide range of stress conditions, and hchA null mutants exhibit a decreased ability to survive in deep stationary phase relative to hchA+ cells. Therefore, we believe it can be a strong indicator of the stationary phase. | ||
| + | [[File:HchA mRNA expression.png|400px|thumb|center|This is the hchA mRNA expression-Time graph.]] | ||
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Latest revision as of 13:28, 10 October 2022
hchA promoter
hchA is the structural gene encoding Hsp31 (protein/nucleic acid deglycase). It is a stationary phase-inducible gene. In exponentially growing cells, the nucleoid-binding protein H-NS downregulates Hsp31 synthesis, while entry into the stationary phase leads to enhanced hchA transcription from its σS dependent promoter. hchA performs a protective function under a wide range of stress conditions, and hchA null mutants exhibit a decreased ability to survive in deep stationary phase relative to hchA+ cells. Therefore, we believe it can be a strong indicator of the stationary phase.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]