Difference between revisions of "Part:BBa K4165063"

 
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A flexible 7 aa Glycine-Serine linker
 
A flexible 7 aa Glycine-Serine linker
  
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===Usage and Biology===
 
===Usage and Biology===
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A flexible linker with G and S aa residues with variable lengths. According to our project, 3 flexible linker required one for our clamps for binding of Tau or amyloid beta with our binding peptides. Second one for flexible linking between clamps and HTRA1 binding peptide. last one for binding our HTRA1 binding peptide with PDZ domain of our protease HTRA1. our linker with length [7 aa GSGSGSG ] was calculated by our team for testing how it would affect interaction of our mentioned parts with each other using Pymol Software.
  
 
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Revision as of 10:03, 8 October 2022


GSGSGSG

A flexible 7 aa Glycine-Serine linker

Usage and Biology

A flexible linker with G and S aa residues with variable lengths. According to our project, 3 flexible linker required one for our clamps for binding of Tau or amyloid beta with our binding peptides. Second one for flexible linking between clamps and HTRA1 binding peptide. last one for binding our HTRA1 binding peptide with PDZ domain of our protease HTRA1. our linker with length [7 aa GSGSGSG ] was calculated by our team for testing how it would affect interaction of our mentioned parts with each other using Pymol Software.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]