Difference between revisions of "Part:BBa K4165139"

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                             Figure 1.: Predicted 3D structure of Synthetic peptide TLKIVW.
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                             Figure 1: Predicted 3D structure of Synthetic peptide TLKIVW.
  
modeled by alphafold2 and apptest.
 
best model obtained from apptest
 
  
 
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<p style=" font-weight: bold; font-size:13px;"> Table 1: Quality assessment parameters of TLKIVW model. </p>
Table 1.: Quality assessment parameters of TLKIVW model.
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Revision as of 16:49, 5 October 2022


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Tau binding peptide targeting the PHF seed of Tau

Sequence and Features Status: 500 Content-type: text/html

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Dry Lab

Modeling

TLKIVW were modeled by AlphaFold2 and Apptest. The best model obtained from Apptest


                            Figure 1: Predicted 3D structure of Synthetic peptide TLKIVW.


Table 1: Quality assessment parameters of TLKIVW model.


References

1.Sievers, S. A., Karanicolas, J., Chang, H. W., Zhao, A., Jiang, L., Zirafi, O., ... & Eisenberg, D. (2011). Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation. Nature, 475(7354), 96-100.