Difference between revisions of "Part:BBa K200000"

Revision as of 08:21, 3 September 2009

Colanic acid global regulator -> RcsB

RcsB is a receiver protein in a two component phosphorelay system, which acts as a positive regulator of a number of genes including capsule genes responsible for colanic acid production. 2 This is via the activation of the ugd/cps operon which is required for capsule synthesis.
Colanic acid is a heteropolymer containing glucose, galactose, fucose, and glucuronic acid.

It is important to note that RcsB is a global regulator found in many Enterobacteria. In Salmonella, up to 38 genes were found to be up-regulated by RcsB including ftsZ which affects the rate of cell division. 1

Usage and Biology

Colanic acid is an exopolysaccharide secreted by some bacterial species to protect themselves from the environment that surrounds them.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
COMPATIBLE WITH RFC[1000]

References

1 pmid=1597415
2 pmid=2404948

</biblio>

@@ Line 2: / Line 2: @@
 <partinfo>BBa_K200000 short</partinfo>
-RcsB is a receiver protein in a two component phosphorelay system, which acts as a positive regulator of the capsule genes resulting in colanic acid production. <cite>2</cite> This is via the activation of the ugd/cps operon which is required for capsule synthesis. <br>
+RcsB is a receiver protein in a two component phosphorelay system, which acts as a positive regulator of a number of genes including capsule genes responsible for colanic acid production. <cite>2</cite> This is via the activation of the ugd/cps operon which is required for capsule synthesis. <br> Colanic acid is a heteropolymer containing glucose, galactose, fucose, and glucuronic acid.
-Colanic acid is a heteropolymer containing glucose, galactose, fucose, and glucuronic acid.
+It is important to note that RcsB is a global regulator found in many Enterobacteria. In Salmonella, up to 38 genes were found to be up-regulated by RcsB including ftsZ which affects the rate of cell division. <cite>1</cite>
-It is important to note that RcsB is a central protein in a series of downstream pathways, including the protein ftsZ that affects cell division. <cite>1</cite>
 ===Usage and Biology===