Difference between revisions of "Part:BBa K4143337"

Revision as of 23:52, 29 September 2022

T4GALA Encapsulin

Encapsulins are protein compartments that exist naturally in a variety of bacteria and archaea, and are composed of a single shell protein that self-assembles and can help to sequester and protect antimicrobial peptides when they are expressed in E.coli. Once assembled, they typically form 25–42 nm diameter icosahedral structures.

Usage and Biology

Encapsulins are protein organelles, that encapsulate cargo proteins which are "targeted to the encapsulin capsid interior via small C-terminal peptides referred to as targeting peptides." (Giessen) They typically function to sequester harmful reactions from the rest of the cell, which means that incompatible reactions can occur in a cell at the same time. The encapsulin system is consists of the encapsulin capsid and core cargo genes, which may also be referred to as the core operon.

Sequence and Features