Difference between revisions of "Part:BBa K4268000"

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[[Image:t-suny-oneonta-t7-virus-structure.svg|500px|thumb|center|Figure 1: A labeled visual detailing the various structures of a T7-like phage]]
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[[File:t-suny-oneonta-t7-virus-structure.svg|500px|thumb|center|Figure 1: A labeled visual detailing the various structures of a T7-like phage]]
  
  

Revision as of 20:13, 25 September 2022


S-TIP37 Head-Tail Connector


Usage and Biology

S-TIP 37 is a T7-like cyanophage that virally infects its host via a lytic life cycle. T7-like phages are characterized by a complex symmetrical structure whose major structures are an icosahedral capsid (head) that houses the phage's virus, six tail-like fibers responsible for attachment to its host, and a "neck" region.

This part belongs to a collection that codes for a "ghost" phage shell that can be used to immobilize or deliver substances, to Synechococcus sp WH8109 or other emerging chassis in synthetic biology and cyanobacterial engineering.


File:T-suny-oneonta-t7-virus-structure.svg
Figure 1: A labeled visual detailing the various structures of a T7-like phage


The Head-Tail Connector codes for the "neck" region of a T7-like phage. The "neck" serves two main purposes, binding the icosahedral capsid to the tail-like fibers and containing the molecular machinery that is responsible for injecting its contents into the target cyanobacteria.


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal NheI site found at 346
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]