Difference between revisions of "Part:BBa K3805525"

Latest revision as of 17:25, 21 October 2021

AgrA

As the response regulator in the two-component signal transduction system (TCST) of Staphylococcus aureus, AgrA will be phosphorylated by AgrC that bounds to AIP previously.The activated AgrA can specifically bind to the upstream of promoter P2 and P3 and activate both of them, thus regulating the transcription and expression of agr related genes.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
COMPATIBLE WITH RFC[1000]

Revision as of 11:35, 30 September 2021 (view source) Registry (Talk \| contribs)		Latest revision as of 17:25, 21 October 2021 (view source) Wangwang (Talk \| contribs)
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−	As a response regulator in the two-component signal transduction system (TCST) of Staphylococcus aureus, AgrA~~, which transmits signals~~ to downstream promoter and then regulates genes expression and transcription, plays an important role in the pathogenesis of S. aureus. phosphorylation agrC transfers the phosphate group to AgrA to make it phosphorylation. The activated AgrA can be specifically ~~bound with~~ the ~~repeat sequence between the downstream~~ promoter ~~RNAII~~ and ~~RNAIII~~, thus regulating the transcription and expression of agr.	+	As the response regulator in the two-component signal transduction system (TCST) of ''Staphylococcus aureus'', AgrA will be phosphorylated by AgrC that bounds to AIP previously.The activated AgrA can specifically bind to the upstream of promoter P2 and P3 and activate both of them, thus regulating the transcription and expression of agr related genes.