Difference between revisions of "Part:BBa K4023001"
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<partinfo>BBa_K4023001 short</partinfo> | <partinfo>BBa_K4023001 short</partinfo> | ||
− | glpF codes for a 28kDa transmembrane glycerol uptake facilitator protein found in E.coli strain. glpF protein catalyze transmembrane diffusion of glycerol and some linear polyhydric alcohols in E.coli. glpF protein also allows Arsenite to be transported into E.coli. This is as Arsenite is protonated at physiological pH and forms As(OH)3 as a major species. As(OH)3 is chemically analogous to glycerol. | + | glpF codes for a 28kDa<sup>1</sup> transmembrane glycerol uptake facilitator protein found in E.coli strain. glpF protein catalyze transmembrane diffusion of glycerol and some linear polyhydric alcohols in E.coli<sup>1</sup>. glpF protein also allows Arsenite to be transported into E.coli. This is as Arsenite is protonated at physiological pH and forms As(OH)3 as a major species. As(OH)3 is chemically analogous to glycerol<sup>2</sup>. |
+ | |||
+ | ===References=== | ||
+ | 1. Fu, D., Libson, A., & Stroud, R. (2002, April). The structure of G1pF, a glycerol conducting channel. In Ion Channels: From Atomic Resolution Physiology to Functional Genomics: Novartis Foundation Symposium 245 (Vol. 245, pp. 51-65). Chichester, UK: John Wiley & Sons, Ltd. | ||
+ | 2. Bhattacharjee, H., Mukhopadhyay, R., Thiyagarajan, S., & Rosen, B. P. (2008). Aquaglyceroporins: ancient channels for metalloids. Journal of biology, 7(9), 1-6. | ||
Revision as of 10:34, 21 October 2021
Optimized glpF
glpF codes for a 28kDa1 transmembrane glycerol uptake facilitator protein found in E.coli strain. glpF protein catalyze transmembrane diffusion of glycerol and some linear polyhydric alcohols in E.coli1. glpF protein also allows Arsenite to be transported into E.coli. This is as Arsenite is protonated at physiological pH and forms As(OH)3 as a major species. As(OH)3 is chemically analogous to glycerol2.
References
1. Fu, D., Libson, A., & Stroud, R. (2002, April). The structure of G1pF, a glycerol conducting channel. In Ion Channels: From Atomic Resolution Physiology to Functional Genomics: Novartis Foundation Symposium 245 (Vol. 245, pp. 51-65). Chichester, UK: John Wiley & Sons, Ltd. 2. Bhattacharjee, H., Mukhopadhyay, R., Thiyagarajan, S., & Rosen, B. P. (2008). Aquaglyceroporins: ancient channels for metalloids. Journal of biology, 7(9), 1-6.
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000INCOMPATIBLE WITH RFC[1000]Illegal BsaI site found at 183