Difference between revisions of "Part:BBa K3805532"

 
 
(One intermediate revision by one other user not shown)
Line 3: Line 3:
 
<partinfo>BBa_K3805532 short</partinfo>
 
<partinfo>BBa_K3805532 short</partinfo>
  
−
Outer membrane protease (OmpT) is a 33.5 kDa aspartyl protease that cleaves at dibasic sites and is thought to function as a defense mechanism for E. coli against cationic antimicrobial peptides secreted by the host immune system.Ompt is one of the four major outer membrane proteases of E. coli, and its protein precursor has a relative molecular mass of 42,000, which is recognized and sheared by the signal skin enzyme during transmembrane, and is processed into a mature outer membrane protease with a relative molecular mass of 40,000, which is secreted into the peripheral lumen of the cell and localized on the outer side of the cell membrane. Since this protease is highly expressed in E. coli and has a secretory effect.
+
As the signal peptide of one of the major outer membrane proteins ompT, it has the potential to induce the secretion of certain proteins. It originally has 19 amino acids and two additional amino residues was added to the C-terminus for better cleavage of the signal peptide.
  
 
<!-- Add more about the biology of this part here
 
<!-- Add more about the biology of this part here

Latest revision as of 10:23, 21 October 2021


OmpT signal peptide

As the signal peptide of one of the major outer membrane proteins ompT, it has the potential to induce the secretion of certain proteins. It originally has 19 amino acids and two additional amino residues was added to the C-terminus for better cleavage of the signal peptide.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]