Difference between revisions of "Part:BBa K3889093"

Latest revision as of 06:51, 20 October 2021

Bacillus subtilis yqcF antitoxin

YqcF antitoxin is a part of type 2 toxin-antitoxin system namely YqcGF from Bacillus subtilis. YqcF binds to YqcG (BBa_K3889025) in order to inhibit the toxin. YqcG is a DNase that can lead to DNA degradation finally causing death due to loss of genetic material.

This is a modified version of BBa_K3507003 specific to our project's assembly. Mutated BgIII site to make assembly compatible part.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
COMPATIBLE WITH RFC[1000]

References

1. Brantl, S., & Müller, P. (2019). Toxin–Antitoxin Systems in Bacillus subtilis. In Toxins (Vol. 11, Issue 5, p. 262). MDPI AG. https://doi.org/10.3390/toxins11050262

@@ Line 3: / Line 3: @@
 <partinfo>BBa_K3889093 short</partinfo>
-Antitoxin for toxin yqcG in Bacillus subtilis
+YqcF antitoxin is a part of type 2 toxin-antitoxin system namely YqcGF from <i>Bacillus subtilis</i>. YqcF binds to YqcG (<partinfo>BBa_K3889025</partinfo>) in order to inhibit the toxin. YqcG is a DNase that can lead to DNA degradation finally causing death due to loss of genetic material.
+This is a modified version of <partinfo>BBa_K3507003</partinfo> specific to our project's assembly. Mutated BgIII site to make assembly compatible part.
 <!-- Add more about the biology of this part here
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 <partinfo>BBa_K3889093 parameters</partinfo>
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+===References===
+. Brantl, S., & Müller, P. (2019). Toxin–Antitoxin Systems in Bacillus subtilis. In Toxins (Vol. 11, Issue 5, p. 262). MDPI AG. https://doi.org/10.3390/toxins11050262