Difference between revisions of "Part:BBa K3861003"

Revision as of 13:08, 17 October 2021

ThyA CDS

hilA, together with hilC and hilD, are global regulators and control the expression of the Salmonella pathogenicity island I(SPI-1) genes in S. typhimurium on which the SPI-1 T3SS injectisome is encoded (Widmaier et al., 2009). Over 25 genes that are needed for host invasion are located on the SPI-1 (Darwin and Miller, 1999). Also, hilA activates SPI-1 operon mediated by the prg and inv promoters (Bajaj and Lee et al., 1995; Bajaj et al., 1996). hilA controls SPI genes in response to enviromental needs like pH and oxygen levels (Ahmer et al., 1999; Bajaj et al., 1996, Main-Hester et al., 2008).

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
COMPATIBLE WITH RFC[1000]

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-<i>hilA</i>, together with <i>hilC</i> and <i>hilD</i>, are global regulators and control the expression of the  <i>Salmonella</i> pathogenicity island I(SPI-1) genes in <i>S</i>. typhimurium on which the SPI-1 T3SS injectisome is encoded (Widmaier et al., 2009). Over 25 genes that are needed for host invasion are located on the SPI-1 (Darwin and Miller, 1999). Also, <i>hilA</i> activates SPI-1 operon mediated by the prg and inv promoters (Bajaj and Lee et al., 1995; Bajaj et al., 1996).<i>hilA</i> controls <i>SPI</i> genes in response to enviromental needs like pH and oxygen levels (Ahmer et al., 1999; Bajaj et al., 1996, Main-Hester et al., 2008).
+<i>hilA</i>, together with <i>hilC</i> and <i>hilD</i>, are global regulators and control the expression of the  <i>Salmonella</i> pathogenicity island I(SPI-1) genes in <i>S</i>. typhimurium on which the SPI-1 T3SS injectisome is encoded (Widmaier et al., 2009). Over 25 genes that are needed for host invasion are located on the SPI-1 (Darwin and Miller, 1999). Also, <i>hilA</i> activates SPI-1 operon mediated by the prg and inv promoters (Bajaj and Lee et al., 1995; Bajaj et al., 1996). <i>hilA</i> controls <i>SPI</i> genes in response to enviromental needs like pH and oxygen levels (Ahmer et al., 1999; Bajaj et al., 1996, Main-Hester et al., 2008).
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